PFAS Extraction in Compliance with EPA 1633A

Extraction of PFAS compounds from solids is a common challenge for many laboratories.

Sample preparation is a critical step in the entire analysis workflow as it is time-consuming, labor intensive and error prone. EPA method 1633 rev. A¹ describes extraction using a shaker table technique with multiple transfers between extractions taking a significant amount of time, labor and potential for losses due to repetitive handling. However, EPA 1633 specifically allows improving method parameters such as extraction methodologies per section 9.1 of the method.

The use of microwaves removes the obstacles of the shaker table approach, while providing consistent quality, lower cost and high efficiency in processing, with no regulatory obstacles and processing up to 44 samples per batch.

The XTR-44 rotor is available for PFAS extraction on all ETHOS platform

Your ETHOS platform can accommodate the XTR-44 rotor with no upgrades required.

It achieves full extraction in only 15 minutes, reducing total sample-prep time by up to 70%, significantly lowering labor needs, and simplifying onboarding for new operators. The XTR-44 Extraction Rotor accommodates up to 44 samples per batch, simplifying workflows with commercially available polypropylene centrifuge tubes in various volumes, such as 50 mL. By keeping samples in the same tube throughout the process, this approach minimizes contamination. Additionally, the dedicated microwave configuration meets the requirements of EPA Method 1633.

DESIGNED FOR PFAS-FREE PROCESSING
The rotor design, specifically developed for PFAS, ensures that all vessel components in contact with samples are PFAS-free. Using disposable vessels eliminates the need for cleaning and prevents carryover between runs. This approach significantly reduces contamination risks and streamlines the sample preparation process, while providing excellent recoveries within method requirements.

CONSISTENT PROCESS CONTROL
Advanced sensors in the ETHOS system along with active stirring using non-teflon stir bars deliver precise temperature control and uniformity throughout the extraction process. The easyTEMP sensors and easyCONTROL software ensure uniform conditions across all positions, guaranteeing consistent and reproducible results. The intuitive software provides effortless user experience for routine PFAS sample preparation.